Ask the Pharmacist: The mystery pain of small fiber neuropathy

Ask the Pharmacist: The mystery pain of small fiber neuropathy

There are two types of neuropathy: large fiber neuropathy and small fiber neuropathy.

These are not the same circumstances.

Do not dismiss what I'm about to say because you think it's just "Neuropathy." You could have small fiber neuropathy, and if you ignore it, it will eventually lead to bigger problems throughout your body.

It is very treatable if you read this today and seek proper treatment and assistance.

In SFN, only the small cutaneous nerves are impacted.

SFN differs from typical peripheral neuropathy in that it attacks "small unmyelinated fibers," hence the name "Small fiber neuropathy," and it starts with sensations in the toes and feet.

Most other types of neuropathy result in some degree of demyelination, but because the fibers destroyed in SFN are not myelinated, it does not respond to methylated vitamin B12 as you might expect.

Erythromelalgia is a fairly common condition marked by episodes of redness, heat, pain, or mild swelling, usually in the feet but also in the hands and other parts of the body.

SFN testing requires a skin biopsy, and there are some fantastic new test kits that a physician can order.

SFN does not show up on traditional EMG or nerve conduction studies, which is frustrating and perplexing.

SFN can be caused by infections like Lyme disease or shingles, as well as endocrine disorders like diabetes.

Autoimmunity is another common but difficult to pinpoint cause.

SFN is thought to affect 40 percent of fibromyalgia patients to some degree.

The use of SSRI antidepressants is another intriguing cause of this unpleasant condition.

I've written a more in-depth article that covers more symptoms, treatments, and testing options.

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This information is not intended to be used to treat, cure, or diagnose any disease.

Read the original article "Ask the Pharmacist: Small fiber neuropathy's Mysterious Pain" at

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